N=1 Collaborative

Today, individualized medicines are possible.

We are on a mission to make them safe and rapidly accessible to patients worldwide.

Our Story

What started as a race against time for one little girl has turned into a movement that could help solve the global health crisis of rare genetic diseases.

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Our Work

We are advancing critical steps in the development of individualized medicines, keeping the sharing of knowledge, data, safety and experience at the core.

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Who We Are

We are a group of internationally acclaimed doctors, researchers, patients and companies from across the globe who are committed to expanding the field of individualized medicine.

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Upcoming Seminars

Preclinical development of personalized ASO therapeutics using patient-derived organoid systems

October 6, 2025 at 12:30 pm US EDT This presentation will cover our laboratory's ongoing efforts in the areas of personalized and...

Resources & Articles

N1C Gene Registry

At N1C, we aim to advance individualized medicine by connecting the evolving ecosystem. The N1C Gene Registry (Version 1.0) is our first...

A Baby Receives the First Customized CRISPR Treatment

Alice Park ( TIME ) May 15, 2025 G ene therapy has always held enormous promise to correct genetic diseases, but turning that potential...

'Find a way, or make one': How two scientists hope to revitalize CRISPR's rare disease crisis

Ryan Cross ( Endpoint News ) May 8, 2025 Fyodor Urnov had given a version of his speech dozens of times before. Yet as he leaned into the...

N=1 Collaborative

Preclinical development of personalized ASO therapeutics using patient-derived organoid systems

N1C Gene Registry

A Baby Receives the First Customized CRISPR Treatment

'Find a way, or make one': How two scientists hope to revitalize CRISPR's rare disease crisis

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